
Type:MouseIgG
Applications:WB
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H;M;R
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AscitesFluid-AscitesFluid
Immunogen:Full-lengthrecombinanthumanCaspase7protein.
Caspasesarecysteineproteases,expressedasinactiveprecursors,thatmediateapoptosisbyproteolysisofspecificsubstrates.CaspaseshavetheABIlitytocleaveafterasparticacidresidues.Therearetwoclassesofcaspasesinvolvedinapoptosis;initiators(activationbyreceptorcluster)andeffectors(activationbymitochondrialpermeabilitytransition).Proapoptoticsignalsautocatalyticallyactivateinitiatorcaspases,suchasCaspase-8andCaspase-9.Activatedinitiatorcaspasesthenprocesseffectorcaspases,suchasCaspase-3andCaspase-7,whichinturncausecellcollapse.
OtherReagentstoConsider:
Antibodies:
Caspase-2
Caspase-3
Caspase-3,active
Caspase-9
Caspase-10b
Caspase-12
Bcl-2
ApoptosisAntibodies
CaspasesandCathepsins
CancerAntibodies
NeurodegenerativeDisease
Proteins
Bcl-2
AllApoptosisReagents
StemCellReagents