神经组学/Caspase-9/GT15045/100微升-免疫在线蚂蚁淘旗下平台

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商品详细神经组学/Caspase-9/GT15045/100微升

神经组学/Caspase-9/GT15045/100微升

商品编号： GT15045-100ul

品牌： Neuromics INC

市场价： ¥6900.00

美元价： 4140.00

产地：美国(厂家直采)

公司：

产品分类：功能性抗体

公司分类： Functional_antibody

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Type:GoatIgG

Applications:ICC;IHC;WB

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:H

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

Immunogen:Recombinanthumancaspase-9,aa139-330

Image of Caspase-9 antibody, western blot

Caspase-9isacytoplasmicproenzymethatassociateswithbothpro-apoptoticandanti-apoptoticproteins.Itisakeyregulatorofapoptosisandalsofunctionsinembryonicdevelopment.

AlsoknownasICElikeapoptoticprotease6(ICELAP6),apoptoticproteaseMch6,andapoptoticproteaseactivatingfactor3(Apaf3))isamemberofthepeptidasefamilyC14thatcontainsaCARDdomain.Thiscaspaseisactiveasaheterotetramerandhasbeenreportedtohavetwoisoforms.ProCaspase9hasbeenreportedtobeapproximately47kD.Thiscaspaseispresentinthecytosoland,uponactivation,translocatestothemitochondria.Caspase9isinvolvedinthecaspaseactivationcascaderesponsIBLeforapoptosisexecutionandcleaves/activatesCaspase3andCaspase6.Caspase9isinhibitedbythedominantnegativeisoform,BclXL,cIAP1,cIAP2,XIAP,andLivin.ThiscaspasebecomesactivatedwhenrecruitedtoApaf1/cytochromeccomplex,andfollowingcleavagebyApaf1,granzymeB,Caspase3,possiblyCaspase8andCaspase10intolargep37andsmallp10subunits.Caspase9intereactswithBIRC7andhasbeenshowntocleavePARPandvimentin.

Image:Immunoblotsofextractsfrom2x10⁵humanJurkatcellstreatedwithstaurosporine(STS,1μg/mL)fortheindicatedtimes.Sampleswereelectrophoresedon15%gelsandimmunoblottingwaswith1.0μg/mLgoatanti-Caspase-9thatdetectstheprecursorand34and37kDaformsofpro+LSU.

OtherReagentstoConsider:

Antibodies:

Caspase-3

Caspase-3,active

Caspase-7

Caspase-9

Caspase-10b

Caspase-12

Bcl-2

Vimentin-Catalog#:CH230101

Vimentin-Catalog#CH22108

ApoptosisAntibodies

CaspasesandCathepsins

CancerAntibodies

NeurodegenerativeDisease

Proteins

Bcl-2

AllApoptosisReagents

StemCellReagents

品牌介绍

NeuromicsNeuromics公司是一家著名的神经科学产品和神经干细胞产品专业供应室，提供一系列高品质新蛋白的抗体、神经干细胞及培养基、神经干细胞扩增及分化试剂盒、干细胞抗体、神经和前体细胞流式分型试剂等。Our unique value is based on providing reagents that are thoroughly tested and characterized. We stand behind our products. If our reagents or cells do not meet expectations, we will fix it. We will either send equal replacement quantities or refund your money. Your satisfaction and feedback are important to our mutual success.产品列表：No.品牌货号名称规格1NeuromicsHMP201GFP Expressing Human Brain Astrocytes500,000 Cells - Frozen2NeuromicsNP4200NeuroProgenitors1,000,000 Cells3NeuromicsHEC02Human Brain Microvascular Endothelial Cells500,000+ Cells frozen4NeuromicsSC00A1-CMHuman Cardiomyocytes500,000 Cells5NeuromicsSC00A8-500Fluorescein Labeled Human Chondrocytes-HCS500,000 Cells6NeuromicsCAF05Human Colorectal Tumor CAFs1,000,000 cells7NeuromicsNS36100Neurosphere Tissue1 Million Cells8NeuromicsPC35120Amygdala1 Amygdala9NeuromicsFBS001FBS - Fetal Bovine Serum100 mL10NeuromicsPC00B7Additional Human alpha Motor Neuron Maintaining Media500 mL11NeuromicsKF17362660 Caspase-1 Assay Kit25-50 Tests12NeuromicsPR27005CNTF20 ug13NeuromicsGT15027Presenilin 1100 ug14NeuromicsEL22000pNF-H Sandwich ELISA Kit1 Kit15NeuromicsPL3000296 Well (High)

公司介绍

品牌分类

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