
Type:GoatIgG
Applications:IHC;WB;E
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:Purified,E.coli-derived,recombinanthumanbonemorphogeneticprotein6(rhBMP-6)monomer.

Thereareatleast20structurallyandfunctionallyrelatedBMPs,whicharemembersoftheTGF-betasuperfamily.BMPswereoriginallyidentifiedasproteinregulatorsofcartilageandboneformation.Theyarealsoinvolvedinembryogenesisandmorphogenesisofvarioustissuesandorgans.BMPsregulatethegrowth,differentiation,chemotaxisandapoptosisofvariouscelltypes,includingmesenchymalcells,epithelialcells,hematopoieticcellsandneuronalcells.SimilartootherTGF-betafamilyproteins,BMPsarehighlyconservedacrossanimalspecies.
Thisantibodyshowsapproximately25%cross-reactivitywithrhBMP-3andlessthan1%cross-reactivitywithrhBMP-2,rhBMP-4,rhBMP-5,rhBMP-6andrhBMP-7.
Image:BMP-6 stainingparaffin-embeddedhumanlungtissue.HRP-DABreagents(browncolor)wereusedforthedetection.Tissuesectionswerecounterstainedusinghematoxylin(blue).
OtherReagentstoConsider:AllStemCellReagents
Proteins:
BMP-2,Catalog#:PR15013
BMP-2,CarrierFree
BMP-2,E.ColiExpressed
BMP-2,E.ColiExpressed,CarrierFree
BMP-2,Catalog#:PR27023
BMP-4,Catalog#:PR27024
BMP-4,Catalog#:PR15015
BMP-4,CarrierFree
BMP-6
BMP-7
BMP-RType1A
AllProteins
Antibodies:
BMP-2/4
BMP-3b/GDF-10
BMP-3
BMP-4
BMP-5
BMP-5Monoclonal
BMP-7
BMP-8
GDF-3
GDF-5
BMPProteins
Noggin
AllStemCellReagents
Neurotrophins/GrowthFactors
Neuron/GlialMarkers
Diabetes/ObesityAntibodies
NeurodegenerativeDiseaseAntibodies
CancerAntibodies