Type:RabbitIgG
Applications:IHC;E
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:Syntheticpeptide-KLHconjugatedAminoacids22to35ofhumanBMP10.
Thereareatleast20structurallyandfunctionallyrelatedBMPs,whicharemembersoftheTGF-betasuperfamily.BMPswereoriginallyidentifiedasproteinregulatorsofcartilageandboneformation.Theyarealsoinvolvedinembryogenesisandmorphogenesisofvarioustissuesandorgans.BMPsregulatethegrowth,differentiation,chemotaxisandapoptosisofvariouscelltypes,includingmesenchymalcells,epithelialcells,hematopoieticcellsandneuronalcells.SimilartootherTGF-betafamilyproteins,BMPsarehighlyconservedacrossanimalspecies.
DatastronglysuggestthatBMP10isanessentialcomponentinmodulatingcardiomyocyteproliferationandmaturationduringcardiacventriculardevelopment.andhasrecentlybeenimplicatedinpostnatalcardiachypertrophy.
Image: BMP10 stainingofparaffinembeddedhumancardiactissue.
OtherReagentstoConsider:
AllStemCellReagents
Proteins:
BMP-2,Catalog#:PR15013
BMP-2,CarrierFree
BMP-2,E.ColiExpressed
BMP-2,E.ColiExpressed,CarrierFree
BMP-2,Catalog#:PR27023
BMP-4,Catalog#:PR27024
BMP-4,Catalog#:PR15015
BMP-4,CarrierFree
BMP-6
BMP-7
BMP-RType1A
AllProteins
Antibodies
BMP-1/PCP
BMP-2InducIBLeKinase(BIKE)
BMP-2/4
BMP-3b/GDF-10
BMP-3
BMP-4
BMP-5
BMP-5Monoclonal
BMP-6
BMP-8
Chordin
GDF-3
GDF-5
GDF-8/Myostatin
BMPProteins
Noggin
AllStemCellReagents
Neurotrophins/GrowthFactors
Neuron/GlialMarkers
Diabetes/ObesityAntibodies
NeurodegenerativeDiseaseAntibodies
CancerAntibodies
