
Type:RabbitIgG
Applications:IHC
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:GP;M;Pr;R
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:Wholeserum-lyophilized
Immunogen:SyntheticVIPcoupledtobovinethyroglobulin(BTg)withcarbodiimide(CDI)linker.

VasoactiveIntestinalPeptide(VIP),a28aminoacidpeptideoriginallyisolatedfromporcineduodenum,ispresentnotonlyingastrointestinaltissuesbutalsoinneuraltissues,possIBLyasaneurotransmitter,andexhibitsawidevarietyofBIOLOGicalactions.Itbelongstotheglucagonfamily,andintheduodenumisknowntostimulatemyocardialcontractility,causevasodilation,increaseglycogenolysis,lowerarterialbloodpressureandrelaxthesmoothmuscleoftrachea,stomachandgallbladder.EctopicendocrinetumorssecretingVIP(VIPomas)giverisetoraisedplasmalevelsofVIPandareassociatedwithwaterydiarrhea,hypokalemiaandachlorhydriasyndrome.Thisantibodydetectsganglioncellsinboththesuperficialanddeepplexusofthewallofthesmallbowelinhuman.TheVIPproducingtumorsareusuallyneuroblastomasofendocrinetumorsinthepancreas.Itisalsoamodulatorofjointpain.
Image:VIPStainingofratbrain.