
Type:RabbitIgG
Applications:ICC;IF;IHC;WB
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:B;H;M;Pr;R;Rb
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:Asyntheticpeptidetoaninternalregion(withinresidues300-400)ofthehumanLPIN1protein.[Swiss-Prot#Q14693].

Glucosetransportersareintegralmembraneglycoproteinsinvolvedintransportingglucoseintomostcells.Thereareseventypesofglucosetransportcarrierproteins,designatedasGlut1to7.Molecularcloningofglucosetransportershaveidentifiedafamilyofcloselyrelatedgenesthatencodesatleast7proteinsexhibitinghighdegreeofaminoacidhomology(45%to65%),allinthemolecularweightrangeof40to60kDa.Sometransportersexhibitdynamictraffickingbetweenintracellularstoragesitesandplasmamembranesinresponsetovariousstimuli.InsometissuesGlutproteinsareasymmetricallydistributedbetweenapicalandbasolateralmembranes,asinbloodbrainbarrierandbloodtestisbarriers.GLUT1isamajorglucosetransporterinthemammalianbloodbrainbarrier.Itisubiquitous,andispresentathighlevelsinprimateerythrocytesandbrainendothelialcells.
Image: DetectionofGLUT1inparaffinembeddedmouseintestine.ProtocolonDatasheet