
Type:GoatIgG
Applications:ICC;WB
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H;M
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:E.coliderivedrecombinanthumanNeuroD1(Ser154Asp356).Accession#Q13562

NeuroD1(NeurogenicDifferentiationfactor1,alsoknownasBETA2(beta-cellE-boxtransactivator2)isa40kDaprotein,amemberofthebHLHfamily.NeuroD1isahomologoftheDrosophilaatonalgene.
NeuroD1iswidelyexpressedduringdevelopmentinthemammalianbrainandpancreaswhereitactsasatranscriptionalactivator,andbindstoinsulingeneE-box.NeuroD1hasalsobeenreportedtobeadifferentiationfactorinneurogenesis.ChangesinNeuroD1geneexpressionhavebeenlinkedtodiabetesmellitustypeIIandmaturity-onsetdiabetesoftheyoungtypeVI.NeuroD1expressioncanbeinducedbyglucoseinbetacells.
Images:NeuroD1stainingofimmersionfixedbetaTC-6mousebetacellinsulinomacellline at10µg/mLfor3hoursatroomtemperature.CellswerestainedusingtheFluoro-labeled™557-conjugatedAnti-GoatIgGSecondaryAntibody(red)andcounterstainedwithDAPI(blue).ProtocolonDatasheet.