
Type:GoatIgG
Applications:ICC;WB;E
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid

TheSOX(SRY-boxcontaininggene)genefamilyencodesagroupoftranscriptionfactorsdefinedbytheconservedhighmotilitygroup(HMG)DNA-bindingdomain.Theyareinvolvedintheregulationofembryonicdevelopmentandinthedeterminationofcellfate.
SOX17isamemberoftheSOXfamilyoftranscriptionfactorsthatbindDNAviaahighmobilitygroup(HMG)domain.SOX17issuggestedtoplayanimportantroleinendodermdevelopment.
Image:SOX17 stainingof endodermalcellsderivedfromhumanembyronicstemcells.CellswerestainedusingRhodamineRed-conjugateddonkeyanti-goatsecondaryantibody andcounterstainedusingFluoroNissl(green).CourtesyofDr.Jong-HoonKimandDr.RonMcKayfromtheNationalInstituteofNeurologicalDisordersandStroke&StemCellUnitatNIH.
ForflowcytometryusingSOX17see:SBDR-SOCIETYFORBIOMEDICALDIABETESRESEARCH
TurningHumanEpidermisIntoPancreaticEndoderm.
Sox17:CustomerPublications