
Type:RabbitIgG
Applications:IHC;WB;IP
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H;M;R
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:C-terminalfusionproteinrepresentingaminoacids1253-1391ofratNMDAR2B.

Theionchannelsactivatedbyglutamatearedividedintotwoclasses.ThosethataresensitivetoN-methyl-D-aspartate(NMDA)aredesignatedNMDAreceptors(NMDAR)whilethoseactivatedbykainateanda-amino-3-hydroxy-5-methyl-4-isoxalonepropionicacid(AMPA)areknownaskainate/AMPAreceptors(K/AMPAR).NMDAreceptorsareamongthemoststudiedreceptorsinneurosciencebecausetheyareinvolvedinneuronalcelldevelopmentandplasticity,acellularcorrelateforlearning.NMDAreceptorsarealsoimplicatedinseveraldisordersofthecentralnervoussystemincludingepilepsyandischemicneuronalcelldeath.NMDAreceptorsalsoappeartobeatargetforethanolatphysiologicalconcentrationsandthereforemayplayasignificantroleinalcoholism.
Image: NMDAReceptor2BWesternBlot:RatHippocampus.
RelatedReagentstoConsider:
NMDAReceptor1,N1
NMDAReceptor2A
NMDANR1Pan
phospho-NMDAReceptor1(Ser890)
Phospho-NMDAReceptor1(Ser896)
mGluRandGluRs
GABAReceptors
AllNeurotransmissionResearchAntibodies
Neuron/GlialMarkers
PrimaryNeuronsandAstrocytes