Neuromics/alpha Synuclein/MO15053/100 ug

来自 : 发布时间：2025-04-11

Type: Mouse IgG

Applications: WB; E

E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays

Species Reactivity: H

B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All

Format: Protein G Purified - liquid

Immunogen: Recombinant human alpha Synuclein

alpha Synuclein is a member of a family of small, highly conserved proteins, including synuclein-alpha, -beta, and -gamma, and synoretin. These proteins are localized predominantly in the brain, concentrated in presynaptic nerve terminals. Synuclein-alpha is normally a soluble protein. Abnormal synuclein-alpha forms filamentous inclusions (Lewy bodies and Lewy neurites) in several neurodegenerative diseases, including Parkinsons disease (PD), dementia with Lewy bodies, and Alzheimers disease. It is a major component of intracellular inclusions in sporadic PD. Mutations in the synuclein-alpha gene (A53T and A30P) have been reported in several families with autosomal dominant Parkinsonism.